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KMID : 0363220080460060862
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Korean Journal of Dermatology
2008 Volume.46 No. 6 p.862 ~ p.865
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Two Cases of Acneiform Eruption Caused by Epidermal Growth Factor Receptor Inhibitors
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Choi Gyu-Won
Lee Chae-Young
Lee Yeong-Kyu
Kim Hong-Seok
Kim Ki-Ho
Kim Young-Hun
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Abstract
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Epidermal growth factor receptor (EGFR) inhibitors are associated with unique and dramatical dermatological side effects. The most commonly encountered adverse effect is a mild skin toxicity characterized by a sterile follicular and pustular rash that may be treated empirically and usually does not require treatment modification. Secondary adverse reactions seen with anti-EGFR therapy include xerosis, pruritus, paronychia, hair abnormality, and mucositis. According to the Korean literature, there are no reports of acneiform eruption induced by erlotinib (Tarcevaⓡ). We report a case of acneiform eruption induced by cetuximab (Erbituxⓡ) and a case of acneiform eruption induced by erlotinib (Tarcevaⓡ). (Korean J Dermatol 2008;46(6):862∼865)
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KEYWORD
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Cetuximab, Epidermal growth factor receptor inhibitor, Erlotinib
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